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Research overview · For research use only

TB-500

What the research literature on this thymosin beta-4 fragment actually examines — and a side-by-side of vetted vendors so you can source it for laboratory research with confidence.

What is TB-500?

TB-500 is a synthetic peptide based on a fragment of thymosin beta-4 (Tβ4), a naturally occurring protein involved in cell migration and tissue organization. It is frequently studied alongside BPC-157 in tissue-repair research and is sold strictly as a research material — not as a drug, supplement, or product for human use.

Research framing. Everything below describes what published studies have investigated, largely in cell and animal models. It is not health advice, not a description of effects in humans, and not a recommendation to use TB-500. Human clinical evidence is limited, and TB-500 is not approved by the FDA for human consumption.

What the research investigates

Thymosin beta-4 and its fragments have been studied for several decades. In animal and in-vitro models, researchers have examined the molecule's relationship to:

These are areas of laboratory investigation, not established outcomes in people. The translational and clinical picture in humans remains an open research question. For background on thymosin beta-4 biology, see the peer-reviewed literature indexed at PubMed.

TB-500 vs BPC-157

These two are the most-compared compounds in the repair-research space and are often studied together. We break down what the literature examines for each, side by side: BPC-157 vs TB-500 →

Legal status (2026)

TB-500 is unscheduled under the Controlled Substances Act and is sold in the U.S. for research use only. The compounding-regulation landscape shifted in 2026 — read our breakdown of what changed: The 2026 FDA Peptide Reclassification, Explained.

Updated monthly · For research use only

Where to buy TB-500 — compared

Buy directly from vetted research-peptide vendors below. Each product ships from the vendor and is sold strictly for laboratory and research use — not for human consumption. Links are affiliate links, disclosed per FTC guidelines; you pay the same price.

Research use onlyZestyRat Research TB-500 (Thymosin β-4) research vial
ZestyRat Research

TB-500 (Thymosin β-4)

Recovery research
$35.99 starting★ Most purchased
Buy at ZestyRat →
Use code SHAUN10 at checkout — 10% off
Most ordered through this site — every reader order delivered, zero issues reported
Research use onlyCD
CD Biolab

TB-500

Recovery research
$49 / vial★ #2 · US lab
Order at CD Biolab →
99%+ HPLC · COA every batch
US lab · fast domestic shipping · real phone/text support
Research use onlyORB
Orbitrex Peptides

TB-500

Recovery & repair research · ≥99%
$59.99 startingFinnrick A
Buy at Orbitrex →
Use code UNCAGED at checkout — 10% off
Finnrick A · QR-COA every vial · same-day UPS
Research use onlyAC
Amino Club

TB-500

99%+ purity · ISO 17025 COA
$39.99 starting99%+ guaranteed
Buy at Amino Club →
Use code SHAUN22 at checkout
99%+ purity guarantee · ISO 17025 COAs · free ship $150+
Research use onlyGLP-1 Research Lab TB-500 research vial
GLP-1 Research Lab

TB-500

10 mg · ready to ship
$70 /10 mgSpecialist
Buy at GLP-1 Lab →
Free FedEx 2-day cold-chain shipping
GLP-1 specialist · 6-pack $50/vial + free bac water
Research use onlyMP
Midwest Peptide

TB-500 10mg

Recovery research
$49.99 startingLab-tested
Buy at Midwest →
Use code UNCAGED · free shipping · 5% off with Zelle
COA every batch · 4.9★ Trustpilot (166 reviews) · free shipping
Research use onlySP
Spartan Peptides

TB-500

Recovery research
$169 startingCOA-forward
Buy at Spartan →
Signed third-party lab COAs · 60-day cookie
HPLC + mass-spec on every product · documentation-forward
Research use onlyDP
Dynamic Peptides

TB-500 10mg

Recovery research · >99%
$69.99 10mgGMP/ISO
Buy at Dynamic Peptides →
COA with every product · 30-day cookie
HPLC + MS tested >99% · WHO/GMP + ISO 9001:2015 · 24–48hr US ship
Research use onlyPPL
Pinnacle Peptide Labs

TB-500

Recovery & repair research · ≥99%
$49.99 startingcGMP US
Buy at Pinnacle →
US cGMP lab · third-party tested · free ship $149+ · next-day dispatch
Research use onlyAP
Ascension Peptides

TB-500

Triple-tested · premium
$42 startingPremium · account required
Buy at Ascension →
Triple-verified purity · public COA library
The trust benchmark — 4.7★, zero contamination reports
VendorFromPurity3rd-party COAShipping
ZestyRat Research★ Most purchased $35.9999%+Independent · on requestUS domestic Buy →
CD Biolab★ #2 · US lab $4999%+Every batch · on requestUS domestic Buy →
Orbitrex PeptidesFinnrick A $59.99≥99%✓ QR-COA every vialUS · same-day Buy →
GLP-1 Research LabSpecialist $70≥98%✓ HPLC + MSUS · 1–2 days Buy →
Midwest PeptideLab-tested $49.9999%+✓ Every batchUS · free Buy →
Spartan PeptidesCOA-forward $169HPLC✓ Per-productUS Buy →
Amino Club99%+ guaranteed $39.9999%+✓ ISO 17025US · free $150+ Buy →
Dynamic PeptidesGMP/ISO $69.99>99%✓ COA every productUS · 24–48hr Buy →
Pinnacle Peptide LabscGMP US $49.99≥99%Independent · COA on requestUS · next-day Buy →
Ascension PeptidesMost trusted $4299.4%✓ Triple-verifiedUS · UPS Buy →

Prices are starting points and change often. Every outbound buy link is an affiliate link, disclosed per FTC guidelines. Products listed are for laboratory and research purposes only — not for human consumption.

Common questions

TB-500 FAQ

Is TB-500 legal to buy?

TB-500 is unscheduled and is sold in the U.S. strictly for research use only. It is not approved for human consumption. See our 2026 regulatory breakdown for the current details.

What is the difference between TB-500 and thymosin beta-4?

TB-500 is a synthetic peptide based on an active fragment/region of the larger, naturally occurring thymosin beta-4 protein. Research literature often uses the two terms in related contexts; they are not identical molecules.

How do I know a TB-500 vendor is legitimate?

Look for batch-specific, third-party Certificates of Analysis (COAs), transparent purity testing, U.S. sourcing, and a real reputation across independent review platforms. Our vendor reviews check all of these.

Does Peptides Uncaged sell TB-500?

No. We're an independent research and comparison resource. We link to vetted third-party vendors and disclose every affiliate relationship.

Sources & further reading

Last reviewed June 2026. By the Peptides Uncaged Research Team.

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