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Research overview · For research use only

GLP-1 Peptides

What the research actually investigates across the GLP-1 receptor-agonist class — semaglutide, tirzepatide, and retatrutide — and a side-by-side of vetted vendors for laboratory sourcing.

What are GLP-1 peptides?

GLP-1 (glucagon-like peptide-1) receptor agonists are a class of peptides studied extensively in metabolic research. They are among the most-searched compounds in the peptide space. Note that several molecules in this class exist as FDA-approved prescription medications in clinical settings; the research-peptide market sells them strictly as research materials — not as drugs, supplements, or products for human use.

Research framing. Everything below describes what published studies and clinical trials have investigated. It is not health advice, not a description of what you should take, and not a recommendation to use any GLP-1 compound. Prescription versions of these molecules should only be used under the care of a licensed clinician.

The three most-studied molecules

The class is best understood by how many receptors each molecule engages:

For the primary research, see the retatrutide Phase 2 trial in the New England Journal of Medicine and the comparative tirzepatide vs semaglutide network meta-analysis (NIH/PMC).

Why this category dominates search

GLP-1 molecules sit at the center of the metabolic-research conversation, which makes them the highest-demand category in the peptide space. That demand is exactly why sourcing quality — verified purity and batch-specific COAs — matters most here.

Legal status (2026)

The compounding landscape for several peptides shifted in 2026. Read our breakdown of the FDA reclassification and what it means for sourcing: The 2026 FDA Peptide Reclassification, Explained.

Updated monthly · For research use only

Where to buy GLP-1 compounds — compared

Buy directly from vetted research-peptide vendors below. Each product ships from the vendor and is sold strictly for laboratory and research use — not for human consumption. Links are affiliate links, disclosed per FTC guidelines; you pay the same price.

Research use onlyZestyRat Research GLP-1 (Semaglutide) research vial
ZestyRat Research

GLP-1 (Semaglutide)

10 / 20 / 30 mg options
$79.99 starting★ Most purchased
Buy at ZestyRat →
Use code SHAUN10 at checkout — 10% off
Most ordered through this site — every reader order delivered, zero issues reported
Research use onlyCD
CD Biolab

Semaglutide

Metabolic / GLP-1 research
$69 / vial★ #2 · US lab
Order at CD Biolab →
99%+ HPLC · COA every batch
US lab · fast domestic shipping · real phone/text support
Research use onlyORB
Orbitrex Peptides

Semaglutide (1G-SGT)

GLP-1 metabolic research · ≥99%
$69.99 startingFinnrick A
Buy at Orbitrex →
Use code UNCAGED at checkout — 10% off
Finnrick A · QR-COA every vial · same-day UPS
Research use onlyAC
Amino Club

GLP-3 (RT)

99%+ purity · ISO 17025 COA
$69.99 starting99%+ guaranteed
Buy at Amino Club →
Use code SHAUN22 at checkout
99%+ purity guarantee · ISO 17025 COAs · free ship $150+
Research use onlyGLP-1 Research Lab Semaglutide (GLP-1) research vial
GLP-1 Research Lab

Semaglutide (GLP-1)

10 mg · ≥99%
$57.50 /10 mgSpecialist
Buy at GLP-1 Lab →
Free FedEx 2-day cold-chain shipping
GLP-1 specialist · 6-pack $50/vial + free bac water
Research use onlyGLP-1 Research Lab Tirzepatide (GLP-1/GIP) research vial
GLP-1 Research Lab

Tirzepatide (GLP-1/GIP)

30 mg · dual agonist
$180 /30 mgBest value
Buy at GLP-1 Lab →
Free FedEx 2-day cold-chain shipping
GLP-1 specialist · 6-pack $50/vial + free bac water
Research use onlyGLP-1 Research Lab Retatrutide (Tri-Agonist) research vial
GLP-1 Research Lab

Retatrutide (Tri-Agonist)

30 mg · triple agonist
$150 /30 mg
Buy at GLP-1 Lab →
Free FedEx 2-day cold-chain shipping
GLP-1 specialist · 6-pack $50/vial + free bac water
Research use onlyMP
Midwest Peptide

GLP-3 RT (Retatrutide)

Metabolic research
$79.99 startingLab-tested
Buy at Midwest →
Use code UNCAGED · free shipping · 5% off with Zelle
COA every batch · 4.9★ Trustpilot (166 reviews) · free shipping
Research use onlySP
Spartan Peptides

GLP-1 (Semaglutide)

Metabolic research
$179 startingCOA-forward
Buy at Spartan →
Signed third-party lab COAs · 60-day cookie
HPLC + mass-spec on every product · documentation-forward
Research use onlyDP
Dynamic Peptides

Semaglutide

GLP-1 metabolic · >99%
$59.99 10mgGMP/ISO
Buy at Dynamic Peptides →
COA with every product · 30-day cookie
HPLC + MS tested >99% · WHO/GMP + ISO 9001:2015 · 24–48hr US ship
Research use onlyPPL
Pinnacle Peptide Labs

Semaglutide (GLP-1)

GLP-1 metabolic research · ≥99%
$49.99 startingcGMP US
See current ranked vendors →
US cGMP lab · third-party tested · free ship $149+ · next-day dispatch
Research use onlyAP
Ascension Peptides

GLP-1 (Sema / Tirz / Reta)

Triple-tested · premium
$65 startingPremium · account required
Buy at Ascension →
Triple-verified purity · public COA library
The trust benchmark — 4.7★, zero contamination reports
VendorFromPurity3rd-party COAShipping
ZestyRat Research★ Most purchased $79.9999%+Independent · on requestUS domestic Buy →
CD Biolab★ #2 · US lab $6999%+Every batch · on requestUS domestic Buy →
Orbitrex PeptidesFinnrick A $69.99≥99%✓ QR-COA every vialUS · same-day Buy →
GLP-1 Research LabSpecialist $57.50≥98%✓ HPLC + MSUS · 1–2 days Buy →
GLP-1 Research LabBest value $180≥98%✓ HPLC + MSUS · 1–2 days Buy →
GLP-1 Research Lab $150≥98%✓ HPLC + MSUS · 1–2 days Buy →
Midwest PeptideLab-tested $79.9999%+✓ Every batchUS · free Buy →
Spartan PeptidesCOA-forward $179HPLC✓ Per-productUS Buy →
Amino Club99%+ guaranteed $69.9999%+✓ ISO 17025US · free $150+ Buy →
Dynamic PeptidesGMP/ISO $59.99>99%✓ COA every productUS · 24–48hr Buy →
Pinnacle Peptide LabscGMP US $49.99≥99%Independent · COA on requestUS · next-day Buy →
Ascension PeptidesMost trusted $6599.4%✓ Triple-verifiedUS · UPS Buy →

Prices are starting points and change often. Every outbound buy link is an affiliate link, disclosed per FTC guidelines. Products listed are for laboratory and research purposes only — not for human consumption.

Common questions

GLP-1 FAQ

What is tirzepatide as a GLP-1 research peptide?

Tirzepatide is a dual GLP-1/GIP receptor agonist — it engages two incretin receptors instead of one, which is why it's among the most-studied molecules in the GLP-1 research-peptide category. In the research market it's sold strictly for laboratory research use only, not for human consumption. When sourcing tirzepatide for research, demand batch-specific third-party COAs and verified purity — our top GLP-1 picks are Onyx Biolabs (independent HPLC + Mass Spec, public COAs) and ZestyRat Research.

What's the difference between semaglutide, tirzepatide, and retatrutide?

They differ by how many receptors they engage. Semaglutide is a single GLP-1 agonist; tirzepatide is a dual GLP-1/GIP agonist; retatrutide is an investigational triple GLP-1/GIP/glucagon agonist. Retatrutide is not FDA-approved as of 2026.

Are GLP-1 peptides legal to buy?

Prescription versions are FDA-approved medications dispensed by clinicians. The research-peptide market sells these molecules strictly for research use only — not for human consumption. Always verify a vendor's COAs and sourcing.

How do I evaluate a GLP-1 research vendor?

Demand batch-specific third-party COAs, transparent purity testing, U.S. sourcing, and a verifiable reputation. Purity matters most in this high-demand category. Our vendor reviews check all of these.

Does Peptides Uncaged sell GLP-1 peptides?

No. We're an independent research and comparison resource. We link to vetted third-party vendors and disclose every affiliate relationship.

Sources & further reading

Last reviewed June 2026. By the Peptides Uncaged Research Team.

New research, new vendor scores — first.

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What it costs today

Vendor pricing moves constantly, and the sticker price on a vial is not the number that matters — cost per milligram is. Our sister index reads all four vendor storefronts directly and normalises every listing, so you can see who is actually cheapest right now.

See current semaglutide prices across four vendors, per milligram ›

Also priced: tirzepatide · retatrutide