Research overview · For research use only

MOTS-c

A mitochondrial-derived peptide studied in metabolic and longevity research.

What is MOTS-c?

MOTS-c is a mitochondrial-derived peptide studied in metabolic and aging research models. It is studied across both the metabolic and longevity research areas and is sold strictly as a research material.

Research framing. Everything below describes what published studies have investigated, largely in cell and animal models. It is not health advice, not a description of effects in humans, and not a recommendation to use MOTS-c. It is not approved by the FDA for human consumption.

What the research investigates

In animal and in-vitro models, researchers have examined this compound's relationship to:

These are areas of laboratory investigation, not established outcomes in people. For primary literature, see PubMed — MOTS-c research.

Category & related compounds

Part of the Metabolic & Weight category. Related: GLP-1 · AOD-9604 · Metabolic & Weight hub

Legal status (2026)

This compound is sold in the U.S. for research use only and is not approved for human consumption. The peptide compounding landscape shifted in 2026 — read our breakdown: The 2026 FDA Peptide Reclassification, Explained.

Updated monthly · For research use only

Where to buy MOTS-c — compared

Buy directly from vetted research-peptide vendors below. Each product ships from the vendor and is sold strictly for laboratory and research use — not for human consumption. Links are affiliate links, disclosed per FTC guidelines; you pay the same price.

Research use onlyZestyRat Research MOTS-c research vial
ZestyRat Research

MOTS-c

Mitochondrial peptide
$59.99 starting★ Most purchased
Buy at ZestyRat →
Use code SHAUN10 at checkout — 10% off
Most ordered through this site — every reader order delivered, zero issues reported
Research use onlyCD
CD Biolab

MOTS-c

Mitochondrial research
$58 / vial★ #2 · US lab
Order at CD Biolab →
99%+ HPLC · COA every batch
US lab · fast domestic shipping · real phone/text support
Research use onlyORB
Orbitrex Peptides

MOTS-c

Mitochondrial research · ≥99%
$49.99 startingFinnrick A
Buy at Orbitrex →
Use code UNCAGED at checkout — 10% off
Finnrick A · QR-COA every vial · same-day UPS
Research use onlyAC
Amino Club

MOTS-C

99%+ purity · ISO 17025 COA
$39.99 starting99%+ guaranteed
Buy at Amino Club →
Use code SHAUN22 at checkout
99%+ purity guarantee · ISO 17025 COAs · free ship $150+
Research use onlyMP
Midwest Peptide

MOTS-C 10mg

Mitochondrial research
$44.99 startingLab-tested
Buy at Midwest →
Use code UNCAGED · free shipping · 5% off with Zelle
COA every batch · 4.9★ Trustpilot (166 reviews) · free shipping
Research use onlySP
Spartan Peptides

MOTS-c

Mitochondrial research
$149 startingCOA-forward
Buy at Spartan →
Signed third-party lab COAs · 60-day cookie
HPLC + mass-spec on every product · documentation-forward
Research use onlyDP
Dynamic Peptides

MOTS-c

Mitochondrial research · >99%
$44.99 startingGMP/ISO
Buy at Dynamic Peptides →
COA with every product · 30-day cookie
HPLC + MS tested >99% · WHO/GMP + ISO 9001:2015 · 24–48hr US ship
Research use onlyPPL
Pinnacle Peptide Labs

MOTS-c

Mitochondrial research · ≥99%
$69.99 startingcGMP US
Buy at Pinnacle →
US cGMP lab · third-party tested · free ship $149+ · next-day dispatch
VendorFromPurity3rd-party COAShipping
ZestyRat Research★ Most purchased $59.9999%+Independent · on requestUS domestic Buy →
CD Biolab★ #2 · US lab $5899%+Every batch · on requestUS domestic Buy →
Orbitrex PeptidesFinnrick A $49.99≥99%✓ QR-COA every vialUS · same-day Buy →
Midwest PeptideLab-tested $44.9999%+✓ Every batchUS · free Buy →
Spartan PeptidesCOA-forward $149HPLC✓ Per-productUS Buy →
Amino Club99%+ guaranteed $39.9999%+✓ ISO 17025US · free $150+ Buy →
Dynamic PeptidesGMP/ISO $44.99>99%✓ COA every productUS · 24–48hr Buy →
Pinnacle Peptide LabscGMP US $69.99≥99%Independent · COA on requestUS · next-day Buy →

Prices are starting points and change often. Every outbound buy link is an affiliate link, disclosed per FTC guidelines. Products listed are for laboratory and research purposes only — not for human consumption.

Common questions

MOTS-c FAQ

Why is MOTS-c in two categories?

It is studied in both metabolic and longevity research models, so it appears under both the Metabolic and Longevity hubs.

How do I know a vendor is legitimate?

Look for batch-specific, third-party Certificates of Analysis (COAs), transparent purity testing, U.S. sourcing, and a real reputation across independent review platforms. Our vendor reviews check all of these.

Does Peptides Uncaged sell MOTS-c?

No. We're an independent research and comparison resource. We link to vetted third-party vendors and disclose every affiliate relationship.

Sources & further reading

Last reviewed June 2026. By the Peptides Uncaged Research Team.

New research, new vendor scores — first.

Join the list for honest peptide breakdowns and ranking updates. No spam, ever.