Research overview · For research use only

MOTS-c

A mitochondrial-derived peptide studied in metabolic and longevity research.

What is MOTS-c?

MOTS-c is a mitochondrial-derived peptide studied in metabolic and aging research models. It is studied across both the metabolic and longevity research areas and is sold strictly as a research material.

Research framing. Everything below describes what published studies have investigated, largely in cell and animal models. It is not health advice, not a description of effects in humans, and not a recommendation to use MOTS-c. It is not approved by the FDA for human consumption.

What the research investigates

In animal and in-vitro models, researchers have examined this compound's relationship to:

These are areas of laboratory investigation, not established outcomes in people. For primary literature, see PubMed — MOTS-c research.

Category & related compounds

Part of the Metabolic & Weight category. Related: GLP-1 · AOD-9604 · Metabolic & Weight hub

Legal status (2026)

This compound is sold in the U.S. for research use only and is not approved for human consumption. The peptide compounding landscape shifted in 2026 — read our breakdown: The 2026 FDA Peptide Reclassification, Explained.

Updated monthly · For research use only

Where to buy MOTS-c — compared

Each vendor below is scored on purity, third-party COAs, shipping, and reputation. Prices are starting points and change often. Every link is an affiliate link and is disclosed.

VendorFromPurity3rd-party COAShipping
ZestyRat ResearchTop pick $—99%+✓ Every batchUS domestic View & buy
Vendor BMost tested $—99%+✓ Triple-verifiedUS domestic View & buy
Vendor C $—99%+✓ On requestUS domestic View & buy

Vendor rows and pricing populate as affiliate partnerships are approved. Products listed are for laboratory and research purposes only — not for human consumption.

Common questions

MOTS-c FAQ

Why is MOTS-c in two categories?

It is studied in both metabolic and longevity research models, so it appears under both the Metabolic and Longevity hubs.

How do I know a vendor is legitimate?

Look for batch-specific, third-party Certificates of Analysis (COAs), transparent purity testing, U.S. sourcing, and a real reputation across independent review platforms. Our vendor reviews check all of these.

Does Peptides Uncaged sell MOTS-c?

No. We're an independent research and comparison resource. We link to vetted third-party vendors and disclose every affiliate relationship.

Sources & further reading

Last reviewed June 2026. By Shaun Tucker, B.A. Psychology, author of The Quiet Close.

New research, new vendor scores — first.

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