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Research overview · For research use only

Semax

An ACTH-fragment-derived peptide studied in neuroprotection research.

What is Semax?

Semax is a synthetic peptide derived from a fragment of ACTH (the 4-10 region) studied in neuroprotective and cognition-related research models. It is sold strictly as a research material.

Research framing. Everything below describes what published studies have investigated, largely in cell and animal models. It is not health advice, not a description of effects in humans, and not a recommendation to use Semax. It is not approved by the FDA for human consumption.

What the research investigates

In animal and in-vitro models, researchers have examined this compound's relationship to:

These are areas of laboratory investigation, not established outcomes in people. For primary literature, see PubMed — Semax neuroprotection research.

Category & related compounds

Part of the Neurological category. Related: Selank · Dihexa · Neurological hub

Legal status (2026)

This compound is sold in the U.S. for research use only and is not approved for human consumption. The peptide compounding landscape shifted in 2026 — read our breakdown: The 2026 FDA Peptide Reclassification, Explained.

Updated monthly · For research use only

Where to buy Semax — compared

Each vendor below is scored on purity, third-party COAs, shipping, and reputation. Prices are starting points and change often. Every link is an affiliate link and is disclosed.

VendorFromPurity3rd-party COAShipping
ZestyRat ResearchTop pick $—99%+✓ Every batchUS domestic View & buy
Ascension PeptidesMost trusted See site99.4%✓ Triple-verifiedUS · UPS Buy →
Vendor C $—99%+✓ On requestUS domestic View & buy

Vendor rows and pricing populate as affiliate partnerships are approved. Products listed are for laboratory and research purposes only — not for human consumption.

Common questions

Semax FAQ

Is Semax a nootropic?

'Nootropic' is an informal label. Semax is studied in neurological research models; that describes a research area, not a proven human effect.

How do I know a vendor is legitimate?

Look for batch-specific, third-party Certificates of Analysis (COAs), transparent purity testing, U.S. sourcing, and a real reputation across independent review platforms. Our vendor reviews check all of these.

Does Peptides Uncaged sell Semax?

No. We're an independent research and comparison resource. We link to vetted third-party vendors and disclose every affiliate relationship.

Sources & further reading

Last reviewed June 2026. By Shaun Tucker, B.A. Psychology, author of The Quiet Close.

New research, new vendor scores — first.

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