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Research overview · For research use only

Semax

An ACTH-fragment-derived peptide studied in neuroprotection research.

What is Semax?

Semax is a synthetic peptide derived from a fragment of ACTH (the 4-10 region) studied in neuroprotective and cognition-related research models. It is sold strictly as a research material.

Research framing. Everything below describes what published studies have investigated, largely in cell and animal models. It is not health advice, not a description of effects in humans, and not a recommendation to use Semax. It is not approved by the FDA for human consumption.

What the research investigates

In animal and in-vitro models, researchers have examined this compound's relationship to:

These are areas of laboratory investigation, not established outcomes in people. For primary literature, see PubMed — Semax neuroprotection research.

Category & related compounds

Part of the Neurological category. Related: Selank · Dihexa · Neurological hub

Legal status (2026)

This compound is sold in the U.S. for research use only and is not approved for human consumption. The peptide compounding landscape shifted in 2026 — read our breakdown: The 2026 FDA Peptide Reclassification, Explained.

Updated monthly · For research use only

Where to buy Semax — compared

Buy directly from vetted research-peptide vendors below. Each product ships from the vendor and is sold strictly for laboratory and research use — not for human consumption. Links are affiliate links, disclosed per FTC guidelines; you pay the same price.

Research use onlyZestyRat Research Semax research vial
ZestyRat Research

Semax

10 mg · nootropic research
$64.99 starting★ Most purchased
Buy at ZestyRat →
Use code SHAUN10 at checkout — 10% off
Most ordered through this site — every reader order delivered, zero issues reported
Research use onlyCD
CD Biolab

Semax

Neuro research
$48 / vial★ #2 · US lab
Order at CD Biolab →
99%+ HPLC · COA every batch
US lab · fast domestic shipping · real phone/text support
Research use onlySC
Swiss Chems

Semax 30mg

Nootropic research · 99%+
$73.95 startingSerial-verified vial
Buy at Swiss Chems →
3rd-party HPLC · lab report per batch
Scratch-off serial on the lid · card or ACH checkout · 30-day returns on unopened
Research use onlyORB
Orbitrex Peptides

Semax

Nootropic research · ≥99%
$29.99 startingFinnrick A
Buy at Orbitrex →
Use code UNCAGED at checkout — 10% off
Finnrick A · QR-COA every vial · same-day UPS
Research use onlyAC
Amino Club

Semax

99%+ purity · ISO 17025 COA
$29.99 starting99%+ guaranteed
Buy at Amino Club →
Use code SHAUN22 at checkout
99%+ purity guarantee · ISO 17025 COAs · free ship $150+
Research use onlyMP
Midwest Peptide

Semax 10mg

Nootropic research
$39.99 startingLab-tested
Buy at Midwest →
Use code UNCAGED · free shipping · 5% off with Zelle
COA every batch · 4.9★ Trustpilot (166 reviews) · free shipping
Research use onlySP
Spartan Peptides

Semax

Cognitive research
$159 startingCOA-forward
Buy at Spartan →
Signed third-party lab COAs · 60-day cookie
HPLC + mass-spec on every product · documentation-forward
Research use onlyDP
Dynamic Peptides

Semax 10mg

Nootropic research · >99%
$44.99 10mgGMP/ISO
Buy at Dynamic Peptides →
COA with every product · 30-day cookie
HPLC + MS tested >99% · WHO/GMP + ISO 9001:2015 · 24–48hr US ship
Research use onlyPPL
Pinnacle Peptide Labs

Semax

Nootropic research · ≥99%
$59.99 startingcGMP US
See current ranked vendors →
US cGMP lab · third-party tested · free ship $149+ · next-day dispatch
Research use onlyAP
Ascension Peptides

Semax

Triple-tested · premium
$50 startingPremium · account required
Buy at Ascension →
Triple-verified purity · public COA library
The trust benchmark — 4.7★, zero contamination reports
VendorFromPurity3rd-party COAShipping
ZestyRat Research★ Most purchased $64.9999%+Independent · on requestUS domestic Buy →
CD Biolab★ #2 · US lab $4899%+Every batch · on requestUS domestic Buy →
Orbitrex PeptidesFinnrick A $29.99≥99%✓ QR-COA every vialUS · same-day Buy →
Midwest PeptideLab-tested $39.9999%+✓ Every batchUS · free Buy →
Spartan PeptidesCOA-forward $159HPLC✓ Per-productUS Buy →
Amino Club99%+ guaranteed $29.9999%+✓ ISO 17025US · free $150+ Buy →
Dynamic PeptidesGMP/ISO $44.99>99%✓ COA every productUS · 24–48hr Buy →
Pinnacle Peptide LabscGMP US $59.99≥99%Independent · COA on requestUS · next-day Buy →
Ascension PeptidesMost trusted $5099.4%✓ Triple-verifiedUS · UPS Buy →

Prices are starting points and change often. Every outbound buy link is an affiliate link, disclosed per FTC guidelines. Products listed are for laboratory and research purposes only — not for human consumption.

Common questions

Semax FAQ

Is Semax a nootropic?

'Nootropic' is an informal label. Semax is studied in neurological research models; that describes a research area, not a proven human effect.

How do I know a vendor is legitimate?

Look for batch-specific, third-party Certificates of Analysis (COAs), transparent purity testing, U.S. sourcing, and a real reputation across independent review platforms. Our vendor reviews check all of these.

Does Peptides Uncaged sell Semax?

No. We're an independent research and comparison resource. We link to vetted third-party vendors and disclose every affiliate relationship.

Sources & further reading

Last reviewed June 2026. By the Peptides Uncaged Research Team.

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What it costs today

Vendor pricing moves constantly, and the sticker price on a vial is not the number that matters — cost per milligram is. Our sister index reads all four vendor storefronts directly and normalises every listing, so you can see who is actually cheapest right now.

See current Semax prices across four vendors, per milligram ›

Also priced: Selank · DSIP

Related research guides

Best Peptides for Brain Function · Peptides & Dementia / Alzheimer's Research